Still's disease associated with adenovirus infection and defect in adenovirus directed natural killing.
Department of Pediatrics, Carmel Hospital (Faculty of Medicine, Technion-Israel Institute of Technology), Haifa.
Low natural killer (NK) activity towards adenovirus infected fibroblasts was detected in the peripheral blood of a child with Still's disease and was not normalised by the addition of interferon alfa or interleukin 2. NK cytotoxicity directed at K 562 target cells or polio infected fibroblasts was normal. This specific NK deficiency might have contributed to the development of the child's Still's disease.
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