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Annals of the Rheumatic Diseases 1989;48:733-736; doi:10.1136/ard.48.9.733
Copyright © 1989 BMJ Publishing Group Ltd & European League Against Rheumatism.

Isolation and propagation of endothelial cells derived from rheumatoid synovial microvasculature.

C J Jackson, P K Garbett, R M Marks, G Chapman, D H Sonnabend, S R Potter, P M Brooks, L Schrieber

Sydney University Department of Rheumatology, Royal North Shore Hospital, St Leonards, NSW, Australia.

Synovial angiogenesis may play an important part in the destruction of articular cartilage in patients with rheumatoid arthritis (RA). As an important first step towards developing in vitro models of synovial angiogenesis, microvascular endothelial cells have been isolated, purified, and cultured from operative synovial specimens obtained from adult patients with RA.


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This article has been cited by other articles:

  • Scott, P., Bicknell, R (1993). The isolation and culture of microvascular endothelium. J. Cell Sci. 105: 269-273  

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